T淋巴細胞膜蛋白3抗體/TIM3 Antibody |
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產(chǎn)品名稱 ： T淋巴細胞膜蛋白3抗體/TIM3 Antibody
產(chǎn)品類別 ： IVD診斷抗體原料
品 牌 ： GenomeMe
貨 號 ： IHC003
規(guī) 格 ： 0.1ml/1ml
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詳細信息 |
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產(chǎn)品說明 ：
背景描述Description：
T淋巴細胞膜蛋白3(TIM3)存在于T輔助細胞1型淋巴細胞和其他免疫細胞，包括樹突狀細胞和自然殺傷細胞。TIM3在CD4+腫瘤浸潤淋巴細胞中過表達，包括與預后不良相關(guān)的非小細胞肺癌。TIM3最近成為腫瘤免疫治療的潛在靶點。
T-cell Immunoglobulin and Mucin-Domain-Containing Molecule-3 (TIM3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM3 is overexpressed in CD4+ tumor-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. TIM3 has recently emerged as a potential target for cancer immunotherapy.
Specifications：
Clone: IHC003
Source: Mouse Monoclonal
Positive Control: Tonsil
Dilution Range: 1:100 - 1:400
References:
Monney L, et al. Nature. 2002; 415:536-41.
Sánchez-Fueyo A, et al. Nat Immunol. 2003; 4:1093-101.
Anderson AC. Cancer Immun Res. 2014; 2:393–8.
Gao X, et al. PLoS One. 2012; 7:e30676.
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