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HER2/neu抗體 |
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產(chǎn)品名稱 ： HER2/neu抗體
產(chǎn)品類別 ： IVD診斷抗體原料
品 牌 ： GenomeMe
貨 號(hào) ： IHC042
規(guī) 格 ： 0.1ml/1ml
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詳細(xì)信息 |
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純化方式 ：
緩 沖 液 ：
應(yīng)用說(shuō)明 ：
形 態(tài) ：
產(chǎn)品說(shuō)明 ：
背景描述Description：
Her2/Neu(c-erbB-2)原癌基因是一種跨膜受體酪氨酸激酶，臨床上廣泛存在于多種腫瘤中。c-erbB-2蛋白的過(guò)度表達(dá)與乳腺導(dǎo)管癌、肺腺癌和胃腺癌有關(guān)。Her2和p53之間的相關(guān)性也已被證實(shí)，因?yàn)檫@兩種蛋白的過(guò)度表達(dá)與膀胱癌的早期侵襲和轉(zhuǎn)移有關(guān)。
The Her2/Neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number of carcinomas. Overexpression of the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between Her2 and p53 has also been documented, as overexpression of both proteins has been associated with early invasion and metastasis in bladder cancer.
Specifications：
Clone IHC042
Source Mouse Monoclonal
Positive Control Breast Carcinoma
Dilution Range 1:50-1:200
參考文獻(xiàn)References：
Suthipintawong C, et al. Diagn Cytopathol. 1997; 17:127-33.
Alexiev BA, et al. Gen Diagn Pathol. 1997; 142:271-9.
Fernández Aceñero MJ, et al. Gen Diagn Pathol. 1997; 142:289-96.
Koeppen HKW, et al. Histopathology. 2001; 38:96-104.
Moch H, et al. Virchows Arch A Pathol Anat Histopathol. 1993; 423:329-34.
Cetin B, et al. Transl Gastroenterol Hepatol. 2016; 1:59.
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