細(xì)胞角蛋白19抗體/Cytokeratin 19 Antibody |
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產(chǎn)品名稱 ： 細(xì)胞角蛋白19抗體/Cytokeratin 19 Antibody
產(chǎn)品類別 ： IVD診斷抗體原料
品 牌 ： GenomeMe
貨 號(hào) ： IHC019
規(guī) 格 ： 0.1ml/1ml
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詳細(xì)信息 |
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純化方式 ：
緩 沖 液 ：
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產(chǎn)品說明 ：
背景描述Description：
細(xì)胞角蛋白19(CK19)在上皮組織胞漿內(nèi)的細(xì)胞骨架中形成中間絲，并提供機(jī)械支持?？辜?xì)胞角蛋白19染色上皮和上皮惡性腫瘤，如結(jié)腸癌，胃癌，胰腺癌，膽道癌，肝癌和乳腺癌。細(xì)胞角蛋白19是區(qū)分肝細(xì)胞癌和肝內(nèi)膽管細(xì)胞癌的有用指標(biāo)。細(xì)胞角蛋白7、CAM5.21、Ber-Ep4/MOC31、HepPar1和TTF1聯(lián)合染色可促進(jìn)這種分化。細(xì)胞角蛋白19染色也可用于甲狀腺乳頭狀癌的鑒別。
Cytokeratin 19 (CK19) forms intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue and provides mechanical support. Anti-Cytokeratin 19 stains epithelia and epithelial malignancies such as carcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Cytokeratin 19 is a useful marker for distinguishing hepatocellular carcinoma from intrahepatic cholangiocarcinoma. This differentiation is improved when stained in combination with Cytokeratin 7, CAM5.2l, Ber-EP4/MOC31, HepPar1 and TTF1. Cytokeratin 19 staining can also be used to recognize thyroid papillary carcinomas.
Specifications：
Clone IHC019
Source Mouse Monoclonal
Positive Control Bladder, Colon Carcinoma, Colon, Thyroid Carcinoma
Dilution Range 1:50-1:200
參考文獻(xiàn)References：
Jain R, et al. Appl Immunohistochem Mol Morphol. 2010; 18:9-15.
Rosai J. Tumori. 2003; 89:517-9.
de Matos LL, et al. Diagn Pathol. 2012; 7:97.
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