細(xì)胞角蛋白18抗體/Cytokeratin 18 Antibody |
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產(chǎn)品名稱(chēng) : 細(xì)胞角蛋白18抗體/Cytokeratin 18 Antibody
產(chǎn)品類(lèi)別 : IVD診斷抗體原料
品 牌 : GenomeMe
貨 號(hào) : IHC018
規(guī) 格 : 0.1ml/1ml
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詳細(xì)信息 |
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純化方式 :
緩 沖 液 :
應(yīng)用說(shuō)明 :
形 態(tài) :
產(chǎn)品說(shuō)明 :
背景描述Description:
細(xì)胞角蛋白18(Cytokeratin 18,CK18)存在于單層上皮細(xì)胞、腺上皮細(xì)胞和移行上皮細(xì)胞中,而在復(fù)層上皮細(xì)胞中不表達(dá)。CK18通常與細(xì)胞角蛋白8(Cytokeratin 8)結(jié)合,抗細(xì)胞角蛋白18(Anti-Cytokeratin 18)可用于檢測(cè)單純和腺上皮源性腺癌以及低分化鱗癌細(xì)胞。
Cytokeratin 18 (CK18) is present in simple, glandular, and transitional epithelial cells, but is absent in stratified epithelial cells. CK18 usually multimerizes with Cytokeratin 8, and Anti-Cytokeratin 18 is useful for detecting adenocarcinomas of simple and glandular epithelium origin, as well as poorly differentiated squamous carcinoma cells.
Specifications
Clone IHC018
Source Mouse Monoclonal
Positive Control Breast, Breast Carcinoma
Dilution Range 1:50-1:200
參考文獻(xiàn)References:
Moll R. Subcell Biochem. 1998; 31:205-62.
Ku NO, et al. J Clin Invest. 1997; 99:19-23.
Woelfle U, et al. Clin Cancer Res. 2004; 10:2670-4.
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