尾型同源盒轉錄因子2抗體/CDX-2 Antibody |
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產品名稱 ： 尾型同源盒轉錄因子2抗體/CDX-2 Antibody
產品類別 ： IVD診斷抗體原料
品 牌 ： GenomeMe
貨 號 ： IHC402
規(guī) 格 ： 0.1ml/1ml
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詳細信息 |
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純化方式 ：
緩 沖 液 ：
應用說明 ：
形 態(tài) ：
產品說明 ：
背景描述Description：
CDX-2是腸上皮細胞表達的一種與尾相關的同源盒轉錄因子。CDX-2是一種有用的胃腸道腫瘤標記物，可用于確定胃腸道轉移性腺癌和類癌的起源?？笴DX-2可用于鑒別肺腺癌和轉移性大腸腺癌，而卵巢黏液性癌也可與抗CDX-2呈陽性反應，從而限制了與轉移性大腸腺癌的鑒別能力。
CDX-2 is a caudal-related homeobox transcription factor that is expressed by intestinal epithelial cells. CDX-2 is a useful marker for gastrointestinal carcinoma, and for determining the origin of gastrointestinal metastatic adenocarcinoma and carcinoids. Anti-CDX-2 is used for differentiating lung and metastatic colorectal adenocarcinoma, however mucinous ovarian carcinoma also react positively with Anti-CDX-2, thereby limiting the ability to differentiate from metastatic colorectal adenocarcinoma.
Specifications:
Clone IHC402
Source Mouse Monoclonal
Positive Control Colon
Dilution Range 1:50-1:200
參考文獻References：
Suh E, et al. Mol Cell Biol. 1994; 14:7340-51.
Liu Q, et al. Mod Pathol. 2007; 20:1286–97.
Mazziotta RM, et al. Appl Immunohistochem Mol Morphol. 2005; 13:55-60.
Erickson LA, et al. Endocr Pathol. 2004; 15:247-5.
Kaimaktchiev V, et al. Mod Pathol. 2004; 17:1392-9.
Werling RW, et al. Am J Surg Pathol. 2003; 27:303-10.
Scholl C, et al. J Clin Invest. 2007; 117:1037–48.
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