CD57抗體/CD57 Antibody |
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產(chǎn)品名稱 ： CD57抗體/CD57 Antibody
產(chǎn)品類別 ： IVD診斷抗體原料
品 牌 ： GenomeMe
貨 號 ： IHC539
規(guī) 格 ： 0.1ml/1ml
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產(chǎn)品說明 ：
背景描述Description： ClusterofDifferentiation57，CD57又稱NK-1，是一種可在自然殺傷細胞、部分T淋巴細胞和正常外周血單個核細胞、髓系細胞以及多種多肽、脂類和硫酸軟骨素蛋白多糖中檢測到的抗原。CD57是一種神經(jīng)內(nèi)分泌來源的腫瘤標志物，包括嗜鉻細胞瘤、副神經(jīng)節(jié)瘤、類癌和髓母細胞瘤，以及各種神經(jīng)腫瘤，包括神經(jīng)瘤、神經(jīng)纖維瘤、神經(jīng)鞘瘤和顆粒細胞瘤。CD57在神經(jīng)節(jié)細胞瘤和前列腺癌中也有表達?？笴D57抗體用于鑒別結(jié)節(jié)性淋巴細胞性霍奇金淋巴瘤與T細胞/組織細胞豐富的大B細胞淋巴瘤、結(jié)節(jié)性硬化型霍奇金病和濾泡性淋巴瘤。 Cluster of differentiation 57 (CD57), also known as NK-1, is an antigen detectable in natural killer cells, some T-lymphocytes and normal peripheral blood mononuclear cells, myeloid cells, and a variety of polypeptides, lipids, and chondroitin sulfate proteoglycans. CD57 is indicated as a marker for tumors of neuroendocrine origin, including pheochromocytomas, paragangliomas, carcinoid tumor, and medulloblastomas, as well as various neural tumors including neuromas, neurofibromas, schwannomas, and granular cell tumors. CD57 is also detectable in ganglioneuroma and prostate carcinoma. Anti-CD57 is used to distinguish nodular lymphocyte-predominant Hodgkin’s lymphoma from T-cell/histiocyte-rich large B-cell lymphoma, nodular sclerosis Hodgkin’s disease, and follicular lymphoma.
Specifications： Clone IHC539 Source Mouse Monoclonal Positive Control Tonsil Dilution Range 1:50-1:200
參考文獻References： Lanier LL, et al. J Immunol. 1983; 131:1789-96. Ritchie AW, et al. Clin Exp Immunol. 1983; 51:439-47. Caillaud JM, et al. Cancer Res. 1984; 44:4432-9. Tucker, et al. Cell Differ. 1984; 14:223-30. Abo T, et al. Cell Immunol. 1982; 73:376-84. Khoury T, et al. Int J Exp Pathol. 2011; 92:87-96. Boudova L, et al. Blood. 2003; 102:3753-8. Dabbs DJ. 2014: 324. Eiden SV, et al. Hum Pathol. 2002; 33:1126-32. |
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