|
序 列 ： |
H-Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe-Phe-Ala-Met-OH or H-RDFQSFRKMWPFFAM-OH |
| 分 子 式 ： |
C95H132O20N24S2 |
|
分 子 量 ： |
1994.3 g/mol |
|
純 度 ： |
Purity > 95% by HPLC |
|
形 態(tài) ： |
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
|
溶 解： |
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
|
保存條件 ： |
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
| 產(chǎn)品鏈接 ： |
http://www.ABBIOTEC.com/peptides/peptide-p60 |
|
產(chǎn)品說明 ： |
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| 產(chǎn)品描述 ： |
Peptide P60 has demonstrated potential of inhibiting the immunosuppressive activity of murine and human derived regulatory T-cells (Tregs) and enhances the effector T-cell stimulation in vitro by binding to regulatory T-cells specific forkhead/winged helix transcription factor 3 (FOXP3). Peptide P60 can enter the cells to inhibit FOXP3 nuclear translocation and activity on other transcription factors. In vitro, peptide P60 (100 uM) inhibited murine and human-derived Treg and improved effector T cell stimulation. |
