|
序 列 ： |
The synthetic peptide used to raise the antibody Cat. No. 200110 is selected from a sequence within the N-term region of human INSR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| 分 子 式 ： |
C87H138N24O25S1 |
|
分 子 量 ： |
1952.2 g/mol |
|
純 度 ： |
Purity > 80% by HPLC |
|
形 態(tài) ： |
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking e |
|
溶 解： |
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
|
保存條件 ： |
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
| 產(chǎn)品鏈接 ： |
http://www.ABBIOTEC.com/peptides/insr-peptide |
|
產(chǎn)品說明 ： |
|
| 產(chǎn)品描述 ： |
INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance. |
