|
序 列 ： |
Human: H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH or H-SFLLRNPNDKYEPF-OH |
| 分 子 式 ： |
C81H118N20O23 |
|
分 子 量 ： |
1739.96 g/mol |
|
純 度 ： |
Purity > 95% by HPLC |
|
形 態(tài) ： |
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
|
溶 解： |
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
|
保存條件 ： |
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
| 產(chǎn)品鏈接 ： |
http://www.ABBIOTEC.com/peptides/thrombin-receptor-agonist-peptide |
|
產(chǎn)品說(shuō)明 ： |
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| 產(chǎn)品描述 ： |
Thrombin signaling of platelets is mediated by a G protein-coupled protease-activated receptor (PAR). The PAR is activated after thrombin binding and subsequent cleavage of the amino terminal end of the receptor. This new amino terminus acts as a tethered ligand and binds intramolecularly to the body of the PAR, resulting in a transmembrane signal. A synthetic thrombin receptor agonist peptide (TRP) of 6 residues (SFLLRN) corresponding to aa42-47 of the thrombin receptor was found to be as effective as thrombin for Ca2+ mobilization. TRAP can be used instead of thrombin to trigger platelet aggregation and clot retraction. |
