序 列 : |
H-Arg-Gly-Asp-Ser-OH or H-RGDS-OH |
分 子 式 : |
C15H27N7O8 |
分 子 量 : |
433.4 g/mol |
純 度 : |
Purity > 95% by HPLC |
形 態(tài) : |
Each vial contains 10 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
溶 解: |
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
保存條件 : |
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
產(chǎn)品鏈接 : |
http://www.ABBIOTEC.com/peptides/rgds-peptide |
產(chǎn)品說明 : |
|
產(chǎn)品描述 : |
The RGD peptide is the binding motif of fibronectin to cell adhesion molecules. RGD peptide acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering. The RGDS sequence was found initially to promote the attachment of rat kidney fibroblasts to fibronectin. The free RGDS peptide inhibits attachment of cells to fibronectin-coated substrates. The RGDS sequence is also a target for infectious agents (Treponema's syphilis, Mycobacterium's tuberculosis). RGDS can also block fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to erythrocyte membranes. |