|
序 列 ： |
Human: H-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH or H-AQDFVQWLMNT-OH |
| 分 子 式 ： |
C61H89N15O18S1 |
|
分 子 量 ： |
1352.54 g/mol |
|
純 度 ： |
Purity > 95% by HPLC |
|
形 態(tài) ： |
Each vial contains 2 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
|
溶 解： |
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
|
保存條件 ： |
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
| 產(chǎn)品鏈接 ： |
http://www.ABBIOTEC.com/peptides/glucagon-%25255B19-29%25255D-peptide |
|
產(chǎn)品說(shuō)明 ： |
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| 產(chǎn)品描述 ： |
Glucagon [19-29] corresponds to the C-terminal fragment of glucagon, a hormone secreted in the A cells of the islets of Langherans that plays a key role in glucose metabolism and homeostasis. Glucagon [19-29] is a potent Ca2+/Mg2+-ATPase inhibitor. It inhibits secretagogue-induced insulin secretion in beta-cells (IC50<1 pM) and Ca2+/Mg2+-ATPase activity in liver plasma membranes (IC50=0.75 nM). It also contributes to the positive inotropic effect of glucagon in cardiac cells by amplifying the cytosolic Ca2+ signal. |
