克隆類(lèi)型 : |
Rabbit Polyclonal IgG |
免 疫 原 : |
Peptide derived from Hu DNA Ligase 1. |
純化方式 : |
Immunogen affinity purified |
緩 沖 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
產(chǎn)品描述 : |
Eukaryotic DNA ligases are ATP-dependent enzymes that catalyse the joining of single and double-strand DNA breaks, which is an essential final step in DNA replication, recombination and repair. Four biochemically distinct DNA ligases, termed ligases I-IV, have been identified in mammalian cells. DNA ligase I is functionally homologous to the DNA ligase encoded by the Saccharomyces cerevisiae Cdc9 gene. The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is due to DNA ligase I. |
適用物種 : |
Hu, Mo, Rat, Dog, Pig, Cow, Hor |
應(yīng)用說(shuō)明 : |
E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
別 名 : |
DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1; DNLI1_Hu. |
保存條件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
標(biāo) 記 物 : |
PLLABS公司可供應(yīng)生物素、辣根過(guò)氧化物酶、熒光素標(biāo)記抗體 |
產(chǎn)品說(shuō)明 : |
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