| 克隆類型 ： |
Rabbit Polyclonal IgG |
|
免 疫 原 ： |
Peptide derived from Hu HLTF. |
|
純化方式 ： |
Immunogen affinity purified |
|
緩 沖 液 ： |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
產(chǎn)品描述 ： |
Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA. |
| 適用物種 ： |
Hu, Mo, Rat, Dog, Pig, Cow, Hor |
| 應(yīng)用說(shuō)明 ： |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
| 別 名 ： |
DNA-binding protein/plasminogen activator inhibitor 1 regulator; Helicase like transcription factor; HIP116; HIP116A; HLTF 1; HLTF; HLTF_Hu; HLTF1; p113; RING finger protein 80; RNF80; SMARCA3; SNF2-like 3; SNF2L3; Sucrose nonfermenting protein 2 like 3;SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 3; ZBU1. |
| 保存條件 ： |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
| 標(biāo) 記 物 ： |
PLLABS公司可供應(yīng)生物素、辣根過(guò)氧化物酶、熒光素標(biāo)記抗體 |
|
產(chǎn)品說(shuō)明 ： |
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