| 克隆類型 ： |
Rabbit Polyclonal IgG |
|
免 疫 原 ： |
Peptide derived from Hu RUNX1T1/ETO. |
|
純化方式 ： |
Immunogen affinity purified |
|
緩 沖 液 ： |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
產(chǎn)品描述 ： |
RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene. |
| 適用物種 ： |
Hu, Mo, Rat, Chi, Dog, Pig, Hor |
| 應(yīng)用說明 ： |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
| 別 名 ： |
Acute myelogenous leukemia 1 translocation 1 cyclin D related; Acute myelogenous leukemia 1 translocation 1 protein; AML1T1; CBFA2T1; CDR; Core binding factor runt domain alpha subunit 2 translocated to 1; Core binding factor runt domain alpha subunit 2 translocated to 1 cyclin D related; Cyclin D related; Cyclin D related protein; Eight twenty one protein; ETO; ETO protein; MTG 8b; MTG8. MTG8 protein; MTG8b antibody Myeloid translocation gene on 8q22; Protein CBFA2T1; Protein ETO; Protein MTG8; ZMYND2. |
| 保存條件 ： |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
| 標(biāo) 記 物 ： |
PLLABS公司可供應(yīng)生物素、辣根過氧化物酶、熒光素標(biāo)記抗體 |
|
產(chǎn)品說明 ： |
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