克隆類型 : |
Rabbit Polyclonal IgG |
免 疫 原 : |
Peptide derived from human Drebrin. |
純化方式 : |
Immunogen affinity purified |
緩 沖 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
產(chǎn)品描述 : |
The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. |
適用物種 : |
Hu, Mo, Rat, Pig, Cow, Hor |
應用說明 : |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
別 名 : |
Ankyrin repeat and SOCS box 2 containing protein; Ankyrin repeat and SOCS box containing 2; Ankyrin repeat and SOCS box containing protein 2; Ankyrin repeat containing protein ASB2.ASB2_HUMAN |
保存條件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
標 記 物 : |
PLLABS公司可供應生物素、辣根過氧化物酶、熒光素標記抗體 |
產(chǎn)品說明 : |
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