| 克隆類型 ： |
Rabbit Polyclonal IgG |
|
亞 型 ： |
IgG |
|
免 疫 原 ： |
peptide derived from human PKC eta/PRKCL |
|
純化方式 ： |
Immunogen affinity purified |
|
緩 沖 液 ： |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
產(chǎn)品描述 ： |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). |
| 適用物種 ： |
Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor |
|
應用范圍 ： |
E, IHC, IF |
| 應用說明 ： |
E: 1:5000-1:10000 IHC: 1:100-1:500 IF: 1:100-1:500 |
| 別 名 ： |
KPCL_HUMAN; MGC26269; MGC5363; nPKC eta; PKCh; PKCL; PRKCH; PRKCL; Protein kinase C eta; Protein kinase C eta type. |
| 保存條件 ： |
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted. |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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