克隆類型 : |
Rabbit Polyclonal IgG |
亞 型 : |
IgG |
免 疫 原 : |
peptide derived from human DHRS2 |
純化方式 : |
Immunogen affinity purified |
緩 沖 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
產(chǎn)品描述 : |
DHRS2 is a 258 amino acid protein that localizes to the nucleus and belongs to the short-chain dehydrogenase/reductase (SDR) family. Functioning as an NADPH-dependent dicarbonyl reductase, DHRS2 is thought to inhibit cell replication by either converting cortisone in cortisol, or by catalyzing the oxidation of androgen and estrogen. The gene encoding DHRS2 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). |
適用物種 : |
Hu, Mo, Rat |
應(yīng)用范圍 : |
WB,IHC,IF |
應(yīng)用說(shuō)明 : |
WB: 1:500-1:2000 IHC: 1:100-1:500 IF: 1:100-1:500 |
別 名 : |
Dehydrogenase/reductase (SDR family) member 2; Dehydrogenase/reductase member 2; Dehydrogenase/reductase SDR family member 2; Dicarbonyl reductase HEP27; DHRSⅡ; Hep27; HEP27 protein; Protein D; SDR family member; SDR25C1; Short chain alcohol dehydrogenase family member; Short chain dehydrogenase/reductase family 25C member 1. |
保存條件 : |
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted. |
標(biāo) 記 物 : |
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產(chǎn)品說(shuō)明 : |
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