克隆類型 : |
Monoclonal |
亞 型 : |
IgG1 |
免 疫 原 : |
Full length human recombinant protein of human DCXR in HEK293T cell |
純化方式 : |
Immunogen affinity purified |
緩 沖 液 : |
PBS, pH 7.3(1% BSA, 50% glycerol, 0.02% sodium azide) |
產(chǎn)品描述 : |
DCXR is a 244 amino acid member of the short-chain dehydrogenases/reductases family. This peripheral membrane protein catalyzes NADPH-dependent reduction of mulitple sugars, including L-xylulose, to the osmolyte xylitol. Producing xylitol in the renal tubules can prevent osmotic stress. L-xylulose reductase functions as a homotetramer and is expressed highly in kidney, liver and epididymis. Essential pentosuria is the result of a partial deficiency of L-xylulose reductase. Red blood cells of normal individuals contain two L-xylulose reductases: a major and a minor isozyme. Red cells from patients with pentosuria contain only one isozyme. |
適用物種 : |
Hu |
應用范圍 : |
WB, IHC, ICC/IF |
應用說明 : |
WB: 1:2000 IHC: 1:50 ICC/IF: 1:100 |
別 名 : |
DCR; HCR2; HCRII; KIDCR; P34H; PNTSU; SDR20C1; XR |
保存條件 : |
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted. |
標 記 物 : |
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產(chǎn)品說明 : |
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