克隆類型 : |
Mouse Monoclonal Antibody;Clone number:BU63 |
亞 型 : |
Mouse IgG1 |
純化方式 : |
Concentration:0.5 mg/ml |
緩 沖 液 : |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
產(chǎn)品描述 : |
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
適用物種 : |
Hu |
應(yīng)用范圍 : |
FC |
應(yīng)用說(shuō)明 : |
The amount of the reagent is suggested to be used from 20 μL to 5 μL per 100 μL of peripheral blood. |
保存條件 : |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
標(biāo) 記 物 : |
APC |
產(chǎn)品說(shuō)明 : |
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