| 克隆類型 ： |
Mouse Monoclonal Antibody；Clone number：4H11 |
|
亞 型 ： |
Mouse Ig2b |
|
純化方式 ： |
Concentration：0.5 mg/ml |
|
緩 沖 液 ： |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
|
產(chǎn)品描述 ： |
The 4H11 monoclonal antibody reacts with human CD34, also known as mucosialin. CD34 belongs to a protein family which also includes endoglycan and podocalyxin. Members of this family are single pass transmembrane proteins with a heavily glycosylated extracellular and N-terminal mucin domain. CD34 was first identified as an antigen expressed on hematopoietic progenitors, and has since been extensively used as a marker to isolate cells capable of hematopoietic cell engraftment. In spite of this, the function of CD34 remains unresolved. In addition to expression on hematopoietic progenitors, CD34 is expressed on some populations of mesenchymal stem cells, tumor cell lines, and by vascular endothelia in the adult. Epitopes of CD34 have been assigned to three classes (class I, II or III) based on their differential sensitivity to enzymatic cleavage by neuraminidase, chymopapain, or O-glycoprotease. According to this analysis, the 4H11 antibody belongs to class III, indicating that it reacts with a protein epitope. |
| 適用物種 ： |
Hu |
|
應(yīng)用范圍 ： |
FC |
| 應(yīng)用說(shuō)明 ： |
The amount of the reagent is suggested to be used ≤ 1.0 μg per 10^6 cells in 100 μl volume or 100 μl of whole blood. |
| 保存條件 ： |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
| 標(biāo) 記 物 ： |
BIOT |
|
產(chǎn)品說(shuō)明 ： |
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