| 克隆類型 ： |
Mouse Monoclonal Antibody；Clone number：HIB22 |
|
亞 型 ： |
Mouse IgG1 |
|
純化方式 ： |
Concentration：0.5 mg/ml |
|
緩 沖 液 ： |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
|
產(chǎn)品描述 ： |
CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial. |
| 適用物種 ： |
Hu |
|
應(yīng)用范圍 ： |
FC |
| 應(yīng)用說明 ： |
The amount of the reagent is suggested to be used from 20 μL to 5 μL per 100 μL of peripheral blood. |
| 保存條件 ： |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
| 標 記 物 ： |
PE |
|
產(chǎn)品說明 ： |
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