克隆類型 : |
Mouse Monoclonal Antibody;Clone number:HIB22 |
亞 型 : |
Mouse IgG1 |
純化方式 : |
Concentration:0.5 mg/ml |
緩 沖 液 : |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
產(chǎn)品描述 : |
CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial. |
適用物種 : |
Hu |
應(yīng)用范圍 : |
FC |
應(yīng)用說(shuō)明 : |
The amount of the reagent is suggested to be used from 20 μL to 5 μL per 100 μL of peripheral blood. |
保存條件 : |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
標(biāo) 記 物 : |
APC |
產(chǎn)品說(shuō)明 : |
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