| 克隆類型 ： |
Rat Monoclonal Antibody；Clone number：Fib504 |
|
亞 型 ： |
Rat IgG2a |
|
純化方式 ： |
Concentration：0.2 mg/ml |
|
緩 沖 液 ： |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
|
產(chǎn)品描述 ： |
Integrin beta 7 is a 130 kD glycoprotein which associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin alpha 4 beta 7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alpha E beta 7 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. |
| 適用物種 ： |
Mouse |
|
應(yīng)用范圍 ： |
FC |
| 應(yīng)用說明 ： |
The amount of the reagent is suggested to be used ≤ 0.25 μg /10^6 cells in 100 μl |
| 保存條件 ： |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
| 標(biāo) 記 物 ： |
PE |
|
產(chǎn)品說明 ： |
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