| 克隆類型 ： |
Rat Monoclonal Antibody；Clone number：RA3.3A1/6.1 |
|
亞 型 ： |
Rat IgM |
|
純化方式 ： |
Concentration：0.2 mg/ml |
|
緩 沖 液 ： |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
|
產(chǎn)品描述 ： |
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3,and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
| 適用物種 ： |
Mouse |
|
應(yīng)用范圍 ： |
FC |
| 應(yīng)用說明 ： |
The amount of the reagent is suggested to be used ≤ 0.25 μg /10^6 cells in 100 μl |
| 保存條件 ： |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
| 標(biāo) 記 物 ： |
APC |
|
產(chǎn)品說明 ： |
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