| 克隆類型 ： |
Rat Monoclonal Antibody；Clone number：FGK4.5 |
|
亞 型 ： |
Rat IgG2a |
|
純化方式 ： |
Concentration：0.5 mg/ml |
|
緩 沖 液 ： |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
|
產(chǎn)品描述 ： |
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154(gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
| 適用物種 ： |
Mouse |
|
應(yīng)用范圍 ： |
FC |
| 應(yīng)用說明 ： |
The amount of the reagent is suggested to be used ≤ 1.0 μg/10^6 cells in 100 μl |
| 保存條件 ： |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
| 標(biāo) 記 物 ： |
BIOT |
|
產(chǎn)品說明 ： |
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