克隆類型 : |
Rabbit Polyclonal IgG |
免 疫 原 : |
Peptide derived from human Claudin 14. |
純化方式 : |
Immunogen affinity purified |
緩 沖 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
產(chǎn)品描述 : |
The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecules. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-14 is a multi-pass membrane protein that is expressed in liver, kidney and ear. |
適用物種 : |
Hu, Mo, Rat, Pig, Cow, Hor, Guinea Pig |
應(yīng)用說(shuō)明 : |
IHC: 1:200-1:1000 |
別 名 : |
Claudin-14; CLDN14; DFNB29; Human CLDN14 gene; OTTHUMP00000109046; OTTHUMP00000109049; OTTMUSP00000021531; UNQ777/PRO1571. |
保存條件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
標(biāo) 記 物 : |
PLLABS公司可供應(yīng)生物素、辣根過(guò)氧化物酶、熒光素標(biāo)記抗體 |
產(chǎn)品說(shuō)明 : |
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