克隆類型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human IL-15. |
產(chǎn)品描述 : |
Interleukin-15 (IL-15) is a 114 amino acids cytokine that regulates T and natural killer cell activation and proliferation. Human IL-15 shares approximately 97% and 73% amino acid sequence identity with simian and mouse IL-15, respectively. IL-15 was initially isolated from the simian kidney epithelial cell line CV1/EBNA. The cytokines IL-15 and IL-2 share many biological properties and stimulatory activities (T, B, and NK cells). Both IL-15 and IL-2 stimulate mouse CTLL2 cells. In activated peripheral blood T lymphocytes, IL-2 is highly expressed but the expression of IL-15 is not detectable. There is no sequence homology between IL-15 and IL-2, though IL-15 competes for binding sites with IL-2. Both stimulate the growth of cells through the IL-2 receptor. IL-15 mRNA is expressed in many cell types and tissues including adherent peripheral blood mononuclear cells, fibroblasts, and epithelial cells, monocytes, placenta, and skeletal muscle. |
適用物種 : |
H, M, R |
應(yīng)用范圍 : |
WB, E, IHC |
應(yīng)用說(shuō)明 : |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
別 名 : |
IL-15; IL15; Interleukin-15 |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA, 25% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/il-15-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說(shuō)明 : |
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