| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of rat SLC6A4. |
|
產(chǎn)品描述 ： |
SLC6A4 (Solute carrier family 6, member 4), also known as SERT (serotonin transporter), is a monoamine transporter protein. SLC6A4 transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. SLC6A4 is the target of many antidepressant medications, including those of the SSRI class. It is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma. |
| 適用物種 ： |
M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:10,000-1:50,000; WB: 1:2,000-1:10,000; IHC: 1:500-1:1,000 |
| 別 名 ： |
SLC6A4, Sodium-dependent serotonin transporter; 5HT transporter; 5HTT; Solute carrier family 6 member 4; HTT; SERT |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/slc6a4-antibody-0 |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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