| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PIWI-L1. |
|
產(chǎn)品描述 ： |
PIWI-L1 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L1 is thought to play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells as removing PIWI-L1 protein from single germline stem cells significantly decreases the rate of their division. Recent studies have shown that overexpression of PIWI-L1 (as well as other PIWI-like proteins) are potential biomarkers for colon and other cancers. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IF, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IF: 1:50-1:200; IHC: 1:100-1:500 |
| 別 名 ： |
PIWI-L1; PIWI-like 1; PIWIL1; PIWI; MIWI; HIWI |
|
形 態(tài) ： |
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/piwi-l1-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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