克隆類型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within human ZEB1. |
產(chǎn)品描述 : |
ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in postgastrulation embryogenesis. ZEB1 binds to the promoter of several hemapoietic genes, including interleukin-2, CD4, GATA-3, and alpha(4)-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy. |
適用物種 : |
H |
應(yīng)用范圍 : |
E, WB, ICC |
應(yīng)用說明 : |
E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500 |
別 名 : |
ZEB1;Zinc finger E-box binding homeobox 1; BZP; TCF8; AREB6; FECD6; NIL2A; ZFHEP; ZFHX1A; DELTAEF1 |
形 態(tài) : |
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/zeb1-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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