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克隆類型：	Rabbit Polyclonal Antibody
亞　　型：	Rabbit Ig
免疫原：	KLH-conjugated synthetic peptide encompassing a sequence within human TMEM38A.
產(chǎn)品描述：	TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure; the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.
適用物種：	H, M, R
應(yīng)用范圍：	E, WB
應(yīng)用說明：	E: 1:500-1:1,000; WB: 1:100-1:500
別　　名：	TMEM38A; Transmembrane protein 38A; TRIC-A; TRICA; trimeric cation channel type A
形　　態(tài) ：	Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
保存條件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
產(chǎn)品鏈接：	http://www.abbiotec.com/antibodies/tmem38a-antibody
標(biāo) 記物：
產(chǎn)品說明：

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