| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Fibulin 3. |
|
產(chǎn)品描述 ： |
Fibulin 3, also known as epidermal growth factor (EGF)-containing fibulin-like extracellular matrix protein 1 (EFEMP1), is a member of the fibulin family of extracellular glycoproteins, a group of proteins that are widely distributed and frequently associated with vascular and elastic tissues. The fibulin proteins typically contain a tandem array of EGF-like repeats and a fibulin-type COOH-terminal module. Aberrant accumulation of Fibulin 3 in the endoplasmic reticulum of retinal pigment epithelial cells has been shown to be associated with inherited forms of macular degeneration, but the loss of Fibulin 3 expression does not lead to macular degeneration but rather the appearance of hernias due to a reduction of elastic fibers of fascial connective tissue. Recent experiments have shown that expression of Fibulin 3 promotes tumor growth and may thus be a therapeutic target. At least three isoforms of Fibulin 3 are known to exist. This antibody is predicted to not cross-react with other Fibulin proteins. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB, ICC, IF |
| 應用說明 ： |
E: 1:500-1:1,000; WB: 1:1,000-1:2,000; ICC: 1:50-1:200; IF: 1:50-1:200 |
| 別 名 ： |
Fibulin 3; FBLN3; EGF-containing fibulin-like extracellular matrix protein 1; EFEMP1; DHRD; DRAD; FBNL; MLVT; MTLV; S1-5; FIBL-3 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG (1 mg/ml) in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/fibulin-3-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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