| 克隆類型 ： |
Chicken Polyclonal Antibody |
|
亞 型 ： |
Chicken Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within human AP2M1. |
|
產(chǎn)品描述 ： |
The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
AP2M1; Adaptor-related protein complex 2 mu 1; AP-2 mu-1; mu2; AP50; CLAPM1 |
|
形 態(tài) ： |
Each vial contains 0.1 ml IgY in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/ap2m1-antibody |
| 標(biāo) 記 物 ： |
|
|
產(chǎn)品說明 ： |
|
