克隆類型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing the sequence (1-16) of rat Beta Amyloid. |
產(chǎn)品描述 : |
Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. This fragment is the amino terminus (1-16) of beta-amyloid. |
適用物種 : |
M, R |
應(yīng)用范圍 : |
WB, IHC, E |
應(yīng)用說明 : |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
別 名 : |
APP; ABPP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; Protease nexin-II; PN-II; APPI; PreA4; beta-amyloid 1-16 |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/beta-amyloid-1-16-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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