| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Recombinant full length human UCHL1 expressed in E. coli. |
|
產(chǎn)品描述 ： |
Ubiquitin C-terminal hydrolase 1 (UCHL1) cleaves ubiquitin from other molecules. Genetic knockout of UCHL1 in mice results in a motor neuron degeneration similar to the spontaneous gracile axonal dystrophy (gad) mutant mice. Point mutations in the UCHL1 gene are associated with some forms of human Parkinson's disease. Since UCHL1 is heavily expressed in neurons, it is released in large amounts following injury or degeneration. The detection of UCHL1 in CSF and other bodily fluids can be used as a biomarker. |
| 適用物種 ： |
H, R, M, B |
|
應(yīng)用范圍 ： |
E, WB, IF, IHC |
| 應(yīng)用說明 ： |
E: 1:10,000; WB: 1:5,000; IF: 1:500; IHC: 1:500 |
| 別 名 ： |
Ubiquitin carboxyl-terminal hydrolase isozyme L1; UCH-L1; Neuron cytoplasmic protein 9.5; PGP 9.5; PGP9.5; Ubiquitin thioesterase L1; UCHL1 |
|
形 態(tài) ： |
Each vial contains 0.1 ml concentrated culture supernatant with 0.065% sodium azide. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/uchl1-antibody-0 |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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