克隆類型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
Native protein purified from bovine brain. |
產(chǎn)品描述 : |
Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation. Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 9 is the site on synapsin I that is phosphorylated by cAMP-dependent protein kinase and by calcium calmodulin kinase I. Phosphorylation of this site is thought to regulate synaptic vesicle function and neurite outgrowth.
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適用物種 : |
H, M, R |
應(yīng)用范圍 : |
E, WB, IF, IP, IHC |
應(yīng)用說明 : |
E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:2,000; IF: 1:2,000 |
別 名 : |
Synapsin-1; Synapsin I; SYN1 |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09%. Antibody was purified by immunogen affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/synapsin-i-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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