克隆類型 : |
Mouse Monoclonal Antibody |
亞 型 : |
Mouse IgG1 |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of rat GluR2. |
產(chǎn)品描述 : |
The glutamate receptor 1, a homo- or heterotetramer is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Phosphorylation of Ser831 has been linked to synaptic plasticity as well s learning and memory.
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適用物種 : |
M, R |
應(yīng)用范圍 : |
E, WB |
應(yīng)用說明 : |
E: 1:500-1:1,000; WB: 1:1,000 |
別 名 : |
Glutamate receptor 1; GluR-1; AMPA-selective?glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; GluA1; Gria1; GluR1 |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/glur1-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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