| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
Recombinant mouse DsbA-L protein. |
|
產(chǎn)品描述 ： |
Disulfide-bond-A oxidoreductase-like protein (DsbA-L, previously named as GST Kappa) is an adiponectin-interacting protein. DsbA-L is highly expressed in adipose tissue, and its expression level is negatively correlated with obesity in mice and humans. DsbA-L expression in 3T3-L1 adipocytes is stimulated by the insulin sensitizer rosiglitazone and inhibited by the inflammatory cytokine TNFalpha. Polymorphism of DsbA-L gene has recently been implicated in insulin secretion and body fat distribution. DcbA-L expression by RNAi markedly and selectively reduces adiponectin levels and secretion in 3T3-L1 adipocytes. Recent studies identify DsbA-L as a key regulator for adiponectin biosynthesis. |
| 適用物種 ： |
M, H |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:2000; IHC: 1:200 |
| 別 名 ： |
DsbA-L; Disulfide-bond-A oxidoreductase-like protein |
|
形 態(tài) ： |
Each vial contains 0.1 mL of crude serum, 40% glyerol with 0.065% sodium azide. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/dsba-l-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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