| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Recombinant full length human COBRA1 expressed in E. coli. |
|
產(chǎn)品描述 ： |
Cofactor of BRCA1 (negative elongation factor B, NELF-B, COBRA1) is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. COBRA1 can induce chromatin unfolding. |
| 適用物種 ： |
M, H, Rb, R, Sh |
|
應(yīng)用范圍 ： |
E, WB |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:1,000 |
| 別 名 ： |
Negative elongation factor B; NELF-B; Cofactor of BRCA1; COBRA1; KIAA1182; NELFB |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/cobra1-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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