| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of human CSK expressed in E. coli. |
|
產(chǎn)品描述 ： |
Csk (Carboxy-terminal Src kinase) is a ubiquitously expressed nonreceptor tyrosine kinase. Csk negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK. This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk. It is expressed in lungs and macrophages. |
| 適用物種 ： |
H, M, Mk, R |
|
應(yīng)用范圍 ： |
WB, IF |
| 應(yīng)用說(shuō)明 ： |
WB: 1:500-1:2000; IF: 1:200-1:1000; |
| 別 名 ： |
Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL; CSK |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/csk-5f3-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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