| 克隆類型 ： |
Mouse Monoclonal Antibody |
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亞 型 ： |
Mouse IgG1 |
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免 疫 原 ： |
Purified recombinant fragment of human KLF4 expressed in E. coli.
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產(chǎn)品描述 ： |
KLF4 (Krueppel-like factor 4) is a transcription factor, can act both as activator and as repressor. KLF4 binds the 5'-CACCC-3' core sequence of promoters, and also binds to its own promoter region of its own gene and can activate its own transcription. KLF4 regulates the expression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, in preventing their differentiation. POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differenciated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. iPS cells exhibit the morphology and growth properties of ES cells and express ES cell marker genes. |
| 適用物種 ： |
H |
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應(yīng)用范圍 ： |
WB, IHC, IF |
| 應(yīng)用說明 ： |
WB: 1:500-1:2000;
IHC: 1:200-1:1000;
IF: 1:200-1:1000;
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| 別 名 ： |
Krueppel-like factor 4; Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor; KLF4; EZF; GKLF |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/klf4-1e5-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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