| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of human KLHL21 expressed in E. coli.
|
|
產(chǎn)品描述 ： |
KLHL21 (Kelch-like protein 21) protein is part of the ubiquitin-proteasome pathway. It is a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR (KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome. |
| 適用物種 ： |
H |
|
應用范圍 ： |
WB, IHC |
| 應用說明 ： |
WB: 1:500-1:2000; IHC: 1:200-1:1000 |
| 別 名 ： |
KIAA0469; MGC99635; KLHL21; Kelch-like protein 21 |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/klhl21-2h4-antibody |
| 標 記 物 ： |
|
|
產(chǎn)品說明 ： |
|
