| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of human GATA3 expressed in E. coli |
|
產(chǎn)品描述 ： |
GATA3 (GATA binding protein 3) is an enhancer-binding protein containing a zinc finger domain. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. A common TCR regulatory element was identified by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells, macrophages, or HeLa cell lines. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:10000; WB: 1:500-1:2000; IHC: 1:200-1:1000 |
| 別 名 ： |
HDR; Trans-acting T-cell-specific transcription factor GATA-3 ; GATA-binding factor 3 |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/gata3-7b5-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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