| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of human CDKN1B expressed in E. coli. |
|
產(chǎn)品描述 ： |
p27 (Cyclin-dependent kinase inhibitor p27) is a regulator of cell cycle progression. p27 is involved in G1 arrest. P27 is a potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. P27 forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. P27 acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. Defects in CDKN1B are the cause of multiple endocrine neoplasia type 4 (MEN4). Multiple endocrine neoplasia (MEN) syndromes are inherited cancer syndromes of the thyroid. MEN4 is a MEN-like syndrome with a phenotypic overlap of both MEN1 and MEN2. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
WB |
| 應(yīng)用說明 ： |
WB: 1:500-1:2000;
|
| 別 名 ： |
p27; Kip1; p27/kip1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1; CDKN1B; KIP1 |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/cdkn1b-3d8-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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