克隆類型 : |
Mouse Monoclonal Antibody |
亞 型 : |
Mouse IgG1 |
免 疫 原 : |
Purified recombinant fragment of human CLOCK expressed in E. coli.
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產(chǎn)品描述 : |
CLOCK (Circadian locomoter output cycles protein kaput) heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. CLOCK activates transcription of PER1 and PER2. This transcription is inhibited in a feedback loop by PER and CRY proteins. CLOCK has intrinsic histone acetyltransferase activity and this enzymatic function contributes to chromatin-remodeling events implicated in circadian control of gene expression. CLOCK acetylates primarily histones H3 and H4. |
適用物種 : |
H |
應(yīng)用范圍 : |
WB, FC |
應(yīng)用說明 : |
WB: 1:500-1:2000;
FC: 1:200-1:400;
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別 名 : |
Circadian locomoter output cycles protein kaput; hCLOCK; Class E basic helix-loop-helix protein 8; CLOCK; BHLHE8; KIAA0334 |
形 態(tài) : |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
保存條件 : |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/clock-8f7-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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