| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse lgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of human ZBTB7B expressed in E. coli. |
|
產(chǎn)品描述 ： |
ZBTB7B (Zinc finger and BTB domain-containing protein 7B) is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
WB, IF |
| 應(yīng)用說明 ： |
WB: 1:500-1:2000;
IF: 1:200-1:1000;
|
| 別 名 ： |
Zinc finger and BTB domain-containing protein 7B; Krueppel-related zinc finger protein; cKrox; hcKrox; T-helper-inducing POZ/Krueppel-like factor; Zinc finger and BTB domain-containing protein 15; Zinc finger protein 67 homolog; Zfp-67; Zinc finger protein 857B; Zinc finger protein Th-POK ZBTB15; ZFP67; ZNF857B; ZBTB7B |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/zbtb7b-7c12-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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