| 克隆類型 ： |
Mouse Monoclonal Antibody |
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亞 型 ： |
Mouse IgG1 |
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免 疫 原 ： |
Purified recombinant fragment of human SMC1 expressed in E. coli.
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產(chǎn)品描述 ： |
SMC1 (Structural maintenance of chromosomes protein 1A) protein is involved in chromosome cohesion during cell cycle and in DNA repair. Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or SMC1. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, SMC1is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. |
| 適用物種 ： |
H |
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應(yīng)用范圍 ： |
WB, IHC, IF |
| 應(yīng)用說明 ： |
WB: 1:200-1:1000; IF: 1:200-1:1000; IHC: 1:200-1:1000 |
| 別 名 ： |
Structural maintenance of chromosomes protein 1A; SMC protein 1A; -1-alpha; SMC-1A; Sb1.8; SMC1L1; DXS423E; KIAA0178; SB1.8; SMC1; SMC1A |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/smc1-5b6-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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