| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of human TUBB3 expressed in E. coli. |
|
產(chǎn)品描述 ： |
TUBB3 (Tubulin beta 3) is a highly conserved protein with a molecular weight of ~50 kD. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The two main tubulin isoforms, α- and β-tubulin are usually products of separate genes. The β-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III β-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia and stem cell research. Class III β-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
WB, IF, FC |
| 應(yīng)用說明 ： |
WB: 1:500-1:2000;
IF: 1:200-1:1000;
FC: 1:200-1:400;
|
| 別 名 ： |
Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III; TUBB4; TUBB3 |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/tubb3-2e9-antibody |
| 標(biāo) 記 物 ： |
|
|
產(chǎn)品說明 ： |
|
