| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Purified recombinant fragment of NT5E expressed in E. coli. |
|
產品描述 ： |
NT5E (CD73 (Cluster of Differentiation 73)) is an ecto-5'-nucleotidase. NT5E catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. |
| 適用物種 ： |
H |
|
應用范圍 ： |
E, IHC |
| 應用說明 ： |
E: 1:10000-1:20000; IHC: 1:200-1:1000 |
| 別 名 ： |
eN; NT5; CD73; 5'-nucleotidase, ecto (CD73) |
|
形 態(tài) ： |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存條件 ： |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 產品鏈接 ： |
http://www.abbiotec.com/antibodies/nt5e-1d7-antibody |
| 標 記 物 ： |
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產品說明 ： |
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