克隆類型 : |
Mouse Monoclonal Antibody |
亞 型 : |
Mouse IgG2a |
免 疫 原 : |
Purified recombinant fragment of RTN3 expressed in E. coli. |
產(chǎn)品描述 : |
RTN3 (Reticulon 3) is a multi-pass membrane protein. The reticulons are a group of highly conserved proteins with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. RTN3 inhibits BACE1 activity and amyloid precursor protein processing, also may induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. |
適用物種 : |
H |
應(yīng)用范圍 : |
IHC |
應(yīng)用說明 : |
IHC: 1:200-1:1000
|
別 名 : |
Reticulon-3; Neuroendocrine-specific protein-like 2; -like protein 2; Neuroendocrine-specific protein-like II; NSP-like protein II; NSPLII; ASYIP; NSPL2; RTN3 |
形 態(tài) : |
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
保存條件 : |
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/rtn3-10a8-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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